FEATURES

FAMILY

krueppel C2H2-type zinc-finger protein family

DESCRIPTION

Also known as ZBT32_HUMAN, ZBTB32, FAZF, TZFP, ZNF538. DNA-binding protein that binds to the to a 5'-TGTACAGTGT-3' core sequence. May function as a transcriptional transactivator and transcriptional repressor. Probably exerts its repressor effect by preventing GATA3 from binding to DNA. May play a role in regulating the differentiation and activation of helper T-cells (By similarity). Homodimer (via PTB domain). Interacts with the N-terminal of FANCC. Interacts with ZBTB16. Interacts with GATA3 (By similarity).

EXTERNAL LINKS

uniprot
enzyme classification
PhosphoSitePlus

ZBTB32

Zinc finger and BTB domain-containing protein 32

ZBTB32

Molecular Synopsis