FEATURES

FAMILY

DESCRIPTION

Also known as KCMB2_HUMAN, KCNMB2. Regulatory subunit of the calcium activated potassium KCNMA1 (maxiK) channel. Modulates the calcium sensitivity and gating kinetics of KCNMA1, thereby contributing to KCNMA1 channel diversity. Acts as a negative regulator that confers rapid and complete inactivation of KCNMA1 channel complex. May participate in KCNMA1 inactivation in chromaffin cells of the adrenal gland or in hippocampal CA1 neurons. Interacts with KCNMA1 tetramer. There are probably 4 molecules of KCMNB2 per KCNMA1 tetramer.

EXTERNAL LINKS

uniprot
enzyme classification
PhosphoSitePlus

KCNMB2

Calcium-activated potassium channel subunit beta-2

KCNMB2

Molecular Synopsis