FEATURES

FAMILY

DESCRIPTION

Also known as WNT6_HUMAN, WNT6. Ligand for members of the frizzled family of seven transmembrane receptors. Probable developmental protein. May be a signaling molecule which affects the development of discrete regions of tissues. Is likely to signal over only few cell diameters. Together with CAV1 may promote chemoresistance of gastric cancer cells to DNA-damaging anthracycline drugs through the activation of the canonical Wnt receptor signaling pathway. Interacts with PORCN.

EXTERNAL LINKS

uniprot
enzyme classification
PhosphoSitePlus

WNT6

Protein Wnt-6

WNT6

Molecular Synopsis