FEATURES

FAMILY

DESCRIPTION

Also known as KAD5_HUMAN, AK5. Nucleoside monophosphate (NMP) kinase that catalyzes the reversible transfer of the terminal phosphate group between nucleoside triphosphates and monophosphates. Active on AMP and dAMP with ATP as a donor. When GTP is used as phosphate donor, the enzyme phosphorylates AMP, CMP, and to a small extent dCMP. Also displays broad nucleoside diphosphate kinase activity. Monomer. Interacts with YWHAZ (PubMed:16959763).

EXTERNAL LINKS

uniprot
enzyme classification
PhosphoSitePlus

AK5

Adenylate kinase isoenzyme 5

AK5

Molecular Synopsis