FEATURES

FAMILY

DESCRIPTION

Also known as SRRT_ARATH, SE. Acts as a mediator between the cap-binding complex (CBC) and both the pre-mRNA splicing and primary microRNAs (miRNAs) processing machinery. Required for proper processing of primary miRNAs to miRNAs, thereby playing a role in RNA-mediated gene silencing (RNAi) by miRNAs. Does not participate in sense post-transcriptional gene silencing. Acts as a regulator of meristem activity and adaxial leaf fate via the miRNA gene-silencing pathway by regulating the expression of PHB and by limiting the competence of shoot tissue to respond to KNOX expression. Its function is however not limited to miRNA-mediated repression of leaf polarity genes, but rather acts as a general regulator of primary microRNAs processing. Also critical for the accumulation of the trans-acting small interfering RNA (ta-siRNA). Required for pre-mRNA splicing. Interacts with HYL1 (PubMed:16889646, PubMed:16977334). Interacts with RCF3, RS40 and RS41 (PubMed:26227967).

EXTERNAL LINKS

SE

Serrate RNA effector molecule

SE

Molecular Synopsis