DATA SOURCES
| Name | Data types | Version | Last update |
|---|---|---|---|
| cancer.gov | Drug Indications | 2/27/2021 | |
| clinicaltrials.gov | Clinical Trials | 2/27/2021 | |
| PDB | 3D Crystal Structures | 2/23/2021 | |
| UniProt | Proteins | 2021_01 | 2/10/2021 |
| canSAR | Approved Drug Curation | 1/4/2021 | |
| IMEx | Interactions | 11/10/2020 | |
| Phosphosite | Interactions | 11/2/2020 | |
| Other trusted sources and publications | Interactions | 10/14/2020 | |
| ChEMBL | Compounds, Bioactivity Data | ChEMBL_27 | 5/18/2020 |
| CCSB | Interactions | HI-union | 4/8/2020 |
DATA COUNTS
| Type | # |
|---|---|
| Proteins |
20,396 human, 564,407 all species
|
| 3D Structures |
173,663 structures, 509,182 chains
|
| Compounds |
3,128,263 unique structures
|
| Organisms |
2,148
|
| Chemical Bioactivities |
8,039,118 datapoints from 66,066 studies
|
| Clinical Trials |
368,905
|
| Cancer studies |
TCGA: 33
ICGC: 61
|
| Samples |
Primary: 19,244
Metastasized: 1,782
Pediatric: 4,211
|
| Interactions by host |
1,001,674 (human)
4,032 (coronavirus-human)
2,429 (Cov2)
1,150 (SARS)
309 (MERS)
144 (other coronavirus)
|
| Interactions by type |
Signalling pathways: 102,818
Enzymatic reactions: 8,831
Direct binding: 138,107
In same complex: 388,337
Transcriptional: 117,420
Drug Synergies: 12,118
Low confidence complex: 238,240
|