(PDB: 3KUJ structure)
Classic translation factor GTPase family

FEATURES

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Members	Human proteins	All
Members	20	4143
Drug targets	0	0
With known 3D structures	7	73
With tested compounds	3	4
With active compounds (<100nM)	2	2
With mutations reported	19	19

Classic translation factor GTPase family

Lineage

Superfamily TRAFAC class translation factor GTPase superfamily (22 members)

2 families

Family Classic translation factor GTPase family

2 members not classified in subfamilies

8 subfamilies

Subfamily EF-G/EF-2 subfamily

4 members

EEF2 ,EFTUD2 ,GFM1 ,GFM2

Subfamily EF-Tu/EF-1A subfamily

4 members

EEF1A1 ,EEF1A1P5 ,EEF1A2 ,TUFM

Subfamily EIF2G subfamily

2 members

EIF2S3 ,EIF2S3B

Subfamily ERF3 subfamily

2 members

Subfamily GTPBP1 subfamily

2 members

Subfamily IF-2 subfamily

2 members

Subfamily LepA subfamily

1 member

Subfamily SelB subfamily

1 member

Family Bms1-like GTPase family (2 members)

2 subfamilies

Subfamily BMS1 subfamily

1 member

Subfamily TSR1 subfamily

1 member