(PDB: 2M96 structure)
G-protein coupled receptor 1 family

FEATURES

Members	Human proteins	All
Members	723	2496
Drug targets	72	72
With known 3D structures	63	82
With tested compounds	203	542
With active compounds (<100nM)	186	477
With mutations reported	658	658

G-protein coupled receptor 1 family

Lineage

Family G-protein coupled receptor 1 family (724 members)

671 members not classified in subfamilies

11 subfamilies

Subfamily 5-hydroxytryptamine receptor subfamily (1 member)

1 sub-subfamily

Sub-subfamily HTR1A sub-subfamily ( members)

1 member

Subfamily Adrenergic receptor subfamily (9 members)

9 sub-subfamilies

Sub-subfamily ADRA1A sub-subfamily ( members)

1 member

Sub-subfamily ADRA1B sub-subfamily ( members)

1 member

Sub-subfamily ADRA1D sub-subfamily ( members)

1 member

Sub-subfamily ADRA2A sub-subfamily ( members)

1 member

Sub-subfamily ADRA2B sub-subfamily ( members)

1 member

Sub-subfamily ADRA2C sub-subfamily ( members)

1 member

Sub-subfamily ADRB1 sub-subfamily ( members)

1 member

Sub-subfamily ADRB2 sub-subfamily ( members)

1 member

Sub-subfamily ADRB3 sub-subfamily ( members)

1 member

Subfamily Atypical chemokine receptor subfamily (4 members)

4 members

ACKR1 , ACKR2 , ACKR3 , ACKR4

Subfamily Bradykinin receptor subfamily (2 members)

2 sub-subfamilies

Sub-subfamily BDKRB1 sub-subfamily ( members)

1 member

Sub-subfamily BDKRB2 sub-subfamily ( members)

1 member

Subfamily Endothelin receptor subfamily (2 members)

2 sub-subfamilies

Sub-subfamily EDNRA sub-subfamily ( members)

1 member

Sub-subfamily EDNRB sub-subfamily ( members)

1 member

Subfamily FSH/LSH/TSH subfamily (3 members)

3 members

FSHR , LHCGR , TSHR

Subfamily Mas subfamily (9 members)

9 members

Subfamily Muscarinic acetylcholine receptor subfamily (5 members)

5 sub-subfamilies

Sub-subfamily CHRM1 sub-subfamily ( members)

1 member

Sub-subfamily CHRM2 sub-subfamily ( members)

1 member

Sub-subfamily CHRM3 sub-subfamily ( members)

1 member

Sub-subfamily CHRM4 sub-subfamily ( members)

1 member

Sub-subfamily CHRM5 sub-subfamily ( members)

1 member

Subfamily Neurotensin receptor subfamily (2 members)

2 sub-subfamilies

Sub-subfamily NTSR1 sub-subfamily ( members)

1 member

Sub-subfamily NTSR2 sub-subfamily ( members)

1 member

Subfamily Opsin subfamily (11 members)

11 members

Subfamily Vasopressin/oxytocin receptor subfamily (5 members)

5 members