(PDB: 1Z2C structure)
Rho family

FEATURES

Members	Human proteins	All
Members	20	210
Drug targets	0	0
With known 3D structures	12	26
With tested compounds	5	6
With active compounds (<100nM)	1	1
With mutations reported	20	20

Rho family

Lineage

Superfamily small GTPase superfamily (161 members)

10 families

Family Rho family (20 members)

19 members not classified in subfamilies

1 subfamily

Subfamily CDC42 subfamily (1 member)

1 member

Family Arf family (27 members)

27 members

Family Di-Ras family (3 members)

3 members

DIRAS1 , DIRAS2 , DIRAS3

Family Rab family (74 members)

74 members

Family Ran family (1 member)

1 member

Family RasD family (2 members)

2 members

Family Ras family (26 members)

24 members not classified in subfamilies

1 subfamily

Subfamily KappaB-Ras subfamily (2 members)

2 members

NKIRAS1 , NKIRAS2

Family RGK family (4 members)

4 members

GEM , REM1 , REM2 , RRAD

Family Rheb family (2 members)

2 members

Family SAR1 family (2 members)

2 members