1HVY

3D Structure View

CAVITIES

STRUCTURE SETTINGS

LIGANDS

Bioassembly 1HVY_1

Bioassembly 1HVY_2

Chain 1HVY_A

Chain 1HVY_B

Chain 1HVY_C

Chain 1HVY_D

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GENERAL

TITLE

HUMAN THYMIDYLATE SYNTHASE COMPLEXED WITH DUMP AND RALTITREXED, AN ANTIFOLATE DRUG, IS IN THE CLOSED CONFORMATION

DATE LAST MODIFIED

13 Apr 2022

RELEASE

31 Jan 2001

OBSOLETE

CLASSIFICATION

TRANSFERASE

EXPERIMENT TYPE

X-RAY DIFFRACTION

SPACE GROUP

P 1

RESOLUTION RANGE HIGH

1.9

RESOLUTION RANGE LOW

20.09

PUBMED ID

DOI

10.1021/BI002413I

PDBe

LIGANDS

Target Protein	Gene	Expression System	Organism	Synonims	Actions
P04818	--	ESCHERICHIA COLI	HUMAN	--	Mutations
P04818	--	ESCHERICHIA COLI	HUMAN	--	Mutations
P04818	--	ESCHERICHIA COLI	HUMAN	--	Mutations
P04818	--	ESCHERICHIA COLI	HUMAN	--	Mutations

NGL Viewer is used for the molecular visualization.

AS Rose, AR Bradley, Y Valasatava, JM Duarte, A Prlić and PW Rose. NGL viewer: web-based molecular graphics for large complexes. Bioinformatics: bty419, 2018. doi:10.1093/bioinformatics/bty419
AS Rose and PW Hildebrand. NGL Viewer: a web application for molecular visualization. Nucl Acids Res (1 July 2015) 43 (W1): W576-W579 first published online April 29, 2015. doi:10.1093/nar/gkv402