4B70

3D Structure View

CAVITIES

STRUCTURE SETTINGS

LIGANDS

Chain 4B70_A

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GENERAL

TITLE

AMINOIMIDAZOLES AS BACE-1 INHIBITORS: FROM DE NOVO DESIGN TO AB-LOWERING IN BRAIN

DATE LAST MODIFIED

3 Jul 2013

RELEASE

26 Jun 2013

OBSOLETE

CLASSIFICATION

HYDROLASE

EXPERIMENT TYPE

X-RAY DIFFRACTION

SPACE GROUP

P 21 21 21

RESOLUTION RANGE HIGH

1.6

RESOLUTION RANGE LOW

30.56

PUBMED ID

DOI

10.1021/JM3011349

PDBe

LIGANDS

Structure Chain	Target Protein	Gene	Expression System	Organism	Synonims	Actions
	P56817	--	ESCHERICHIA COLI	HUMAN	ASPARTYL PROTEASE 2, ASP2, ASP 2, BETA-SITE AMYLOI ...	Mutations

NGL Viewer is used for the molecular visualization.

AS Rose, AR Bradley, Y Valasatava, JM Duarte, A Prlić and PW Rose. NGL viewer: web-based molecular graphics for large complexes. Bioinformatics: bty419, 2018. doi:10.1093/bioinformatics/bty419
AS Rose and PW Hildebrand. NGL Viewer: a web application for molecular visualization. Nucl Acids Res (1 July 2015) 43 (W1): W576-W579 first published online April 29, 2015. doi:10.1093/nar/gkv402