4CBY

3D Structure View

CAVITIES

STRUCTURE SETTINGS

LIGANDS

Chain 4CBY_A

Chain 4CBY_B

Chain 4CBY_C

Chain 4CBY_D

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GENERAL

TITLE

DESIGN, SYNTHESIS, AND BIOLOGICAL EVALUATION OF POTENT AND SELECTIVE CLASS IIA HDAC INHIBITORS AS A POTENTIAL THERAPY FOR HUNTINGTON'S DISEASE

DATE LAST MODIFIED

7 Feb 2018

RELEASE

11 Dec 2013

OBSOLETE

CLASSIFICATION

HYDROLASE

EXPERIMENT TYPE

X-RAY DIFFRACTION

SPACE GROUP

P 1 21 1

RESOLUTION RANGE HIGH

2.72

RESOLUTION RANGE LOW

83.1

PUBMED ID

DOI

10.1021/JM4011884

PDBe

LIGANDS

Target Protein	Gene	Expression System	Organism	Synonims	Actions
Q9FIJ2	--	ESCHERICHIA COLI	HUMAN	HD4, HDAC4
Q9SMN1	--	ESCHERICHIA COLI	HUMAN	HD4, HDAC4
P56524	--	ESCHERICHIA COLI	HUMAN	HD4, HDAC4	Mutations
Q9FJW4	--	ESCHERICHIA COLI	HUMAN	HD4, HDAC4

NGL Viewer is used for the molecular visualization.

AS Rose, AR Bradley, Y Valasatava, JM Duarte, A Prlić and PW Rose. NGL viewer: web-based molecular graphics for large complexes. Bioinformatics: bty419, 2018. doi:10.1093/bioinformatics/bty419
AS Rose and PW Hildebrand. NGL Viewer: a web application for molecular visualization. Nucl Acids Res (1 July 2015) 43 (W1): W576-W579 first published online April 29, 2015. doi:10.1093/nar/gkv402