4D0W

3D Structure View

CAVITIES

STRUCTURE SETTINGS

LIGANDS

Chain 4D0W_A

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GENERAL

TITLE

PYRROLE-3-CARBOXAMIDES AS POTENT AND SELECTIVE JAK2 INHIBITORS

DATE LAST MODIFIED

24 Apr 2019

RELEASE

23 Jul 2014

OBSOLETE

CLASSIFICATION

TRANSFERASE

EXPERIMENT TYPE

X-RAY DIFFRACTION

SPACE GROUP

C 2 2 21

RESOLUTION RANGE HIGH

1.77

RESOLUTION RANGE LOW

PUBMED ID

DOI

10.1016/J.BMC.2014.06.025

PDBe

LIGANDS

Structure Chain	Target Protein	Gene	Expression System	Organism	Synonims	Actions
	Q9P371	--	SPODOPTERA FRUGIPERDA	HUMAN	JANUS KINASE 2, JAK-2

NGL Viewer is used for the molecular visualization.

AS Rose, AR Bradley, Y Valasatava, JM Duarte, A Prlić and PW Rose. NGL viewer: web-based molecular graphics for large complexes. Bioinformatics: bty419, 2018. doi:10.1093/bioinformatics/bty419
AS Rose and PW Hildebrand. NGL Viewer: a web application for molecular visualization. Nucl Acids Res (1 July 2015) 43 (W1): W576-W579 first published online April 29, 2015. doi:10.1093/nar/gkv402