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GENERAL
TITLE
CATALYTIC FRAGMENT OF MASP-1 IN COMPLEX WITH ITS SPECIFIC INHIBITOR DEVELOPED BY DIRECTED EVOLUTION ON SGCI SCAFFOLD
DATE LAST MODIFIED
27 Jun 2012
RELEASE
25 Apr 2012
OBSOLETE
CLASSIFICATION
HYDROLASE/HYDROLASE INHIBITOR
EXPERIMENT TYPE
X-RAY DIFFRACTION
SPACE GROUP
P 21 21 21
RESOLUTION RANGE HIGH
3.2
RESOLUTION RANGE LOW
46.91
PUBMED ID
DOI
10.1074/JBC.M112.354332
PDBe
4DJZ
LIGANDS
--
Chains
| Structure Chain | Target Protein | Gene | Expression System | Organism | Synonims | Actions |
|---|---|---|---|---|---|---|
| Q02078 | CRARF, CRARF1, MASP1, PRSS5 | ESCHERICHIA COLI | HUMAN | MANNAN-BINDING LECTIN SERINE PROTEASE 1, COMPLEMEN ... | ||
| P48740 | CRARF, CRARF1, MASP1, PRSS5 | ESCHERICHIA COLI | HUMAN | MANNAN-BINDING LECTIN SERINE PROTEASE 1, COMPLEMEN ... | Mutations | |
| P52952 | CRARF, CRARF1, MASP1, PRSS5 | ESCHERICHIA COLI | HUMAN | MANNAN-BINDING LECTIN SERINE PROTEASE 1, COMPLEMEN ... | ||
| P48740 | CRARF, CRARF1, MASP1, PRSS5 | ESCHERICHIA COLI | HUMAN | MANNAN-BINDING LECTIN SERINE PROTEASE 1, COMPLEMEN ... | Mutations | |
| P52952 | Y09605.1 | ESCHERICHIA COLI | DESERT LOCUST | PROTEASE INHIBITOR SGPI-2, SCHISTOCERCA GREGARIACH ... | ||
| P52952 | Y09605.1 | ESCHERICHIA COLI | DESERT LOCUST | PROTEASE INHIBITOR SGPI-2, SCHISTOCERCA GREGARIACH ... |
NGL Viewer is used for the molecular visualization.
- AS Rose, AR Bradley, Y Valasatava, JM Duarte, A Prlić and PW Rose. NGL viewer: web-based molecular graphics for large complexes. Bioinformatics: bty419, 2018. doi:10.1093/bioinformatics/bty419
- AS Rose and PW Hildebrand. NGL Viewer: a web application for molecular visualization. Nucl Acids Res (1 July 2015) 43 (W1): W576-W579 first published online April 29, 2015. doi:10.1093/nar/gkv402