4DRP

3D Structure View

CAVITIES

STRUCTURE SETTINGS

LIGANDS

Chain 4DRP_A

Spin

Focus

Transparency

More Info

GENERAL

TITLE

EVALUATION OF SYNTHETIC FK506 ANALOGS AS LIGANDS FOR THE FK506-BINDING PROTEINS 51 AND 52: COMPLEX OF FKBP51 WITH 2-(3-((R)-3-(3,4- DIMETHOXYPHENYL)-1-((S)-1-(2-((1R,2S)-2-ETHYL-1-HYDROXY-CYCLOHEXYL)- 2-OXOACETYL)PIPERIDINE-2-CARBONYLOXY)PROPYL)PHENOXY)ACETIC ACID FROM COCRYSTALLIZATION

DATE LAST MODIFIED

23 May 2012

RELEASE

16 May 2012

OBSOLETE

CLASSIFICATION

ISOMERASE

EXPERIMENT TYPE

X-RAY DIFFRACTION

SPACE GROUP

P 21 21 21

RESOLUTION RANGE HIGH

1.79

RESOLUTION RANGE LOW

25.386

PUBMED ID

22455444

DOI

10.1021/JM201746X

PDBe

4DRP

LIGANDS

917682

Chains

Structure Chain	Target Protein	Gene	Expression System	Organism	Synonims	Actions
	Q13451	AIG6, FKBP5, FKBP51	ESCHERICHIA COLI	HUMAN	PPIASE FKBP5, 51 KDA FK506-BINDING PROTEIN, 51 KDA ...	Mutations

NGL Viewer is used for the molecular visualization.

AS Rose, AR Bradley, Y Valasatava, JM Duarte, A Prlić and PW Rose. NGL viewer: web-based molecular graphics for large complexes. Bioinformatics: bty419, 2018. doi:10.1093/bioinformatics/bty419
AS Rose and PW Hildebrand. NGL Viewer: a web application for molecular visualization. Nucl Acids Res (1 July 2015) 43 (W1): W576-W579 first published online April 29, 2015. doi:10.1093/nar/gkv402