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GENERAL
TITLE
STRUCTURE OF BACE-1 (BETA-SECRETASE) IN COMPLEX WITH N-((2S,3R)-1-(4- FLUOROPHENYL)-3-HYDROXY-4-((6'-NEOPENTYL-3',4'- DIHYDROSPIRO[CYCLOBUTANE-1,2'-PYRANO[2,3-B]PYRIDIN]-4'-YL)AMINO) BUTAN-2-YL)ACETAMIDE
DATE LAST MODIFIED
2 Jul 2014
RELEASE
10 Oct 2012
OBSOLETE
CLASSIFICATION
HYDROLASE/HYDROLASE INHIBITOR
EXPERIMENT TYPE
X-RAY DIFFRACTION
SPACE GROUP
P 61 2 2
RESOLUTION RANGE HIGH
2.5
RESOLUTION RANGE LOW
20
PUBMED ID
DOI
10.1021/ML3000148
PDBe
4DUS
Chains
| Structure Chain | Target Protein | Gene | Expression System | Organism | Synonims | Actions |
|---|---|---|---|---|---|---|
| P08254 | BACE1, BACE, KIAA1149 | ESCHERICHIA COLI | HUMAN | ASPARTYL PROTEASE 2, ASP2, ASP 2, BETA-SITE AMYLOI ... |
NGL Viewer is used for the molecular visualization.
- AS Rose, AR Bradley, Y Valasatava, JM Duarte, A Prlić and PW Rose. NGL viewer: web-based molecular graphics for large complexes. Bioinformatics: bty419, 2018. doi:10.1093/bioinformatics/bty419
- AS Rose and PW Hildebrand. NGL Viewer: a web application for molecular visualization. Nucl Acids Res (1 July 2015) 43 (W1): W576-W579 first published online April 29, 2015. doi:10.1093/nar/gkv402