4E28

3D Structure View

CAVITIES

STRUCTURE SETTINGS

LIGANDS

Bioassembly 4E28_1

Chain 4E28_A

Spin

Focus

Transparency

GENERAL

TITLE

STRUCTURE OF HUMAN THYMIDYLATE SYNTHASE IN INACTIVE CONFORMATION WITH A NOVEL NON-PEPTIDIC INHIBITOR

DATE LAST MODIFIED

15 Nov 2017

RELEASE

14 Nov 2012

OBSOLETE

CLASSIFICATION

TRANSFERASE/TRANSFERASE INHIBITOR

EXPERIMENT TYPE

X-RAY DIFFRACTION

SPACE GROUP

P 31 2 1

RESOLUTION RANGE HIGH

2.3

RESOLUTION RANGE LOW

PUBMED ID

DOI

10.1021/JM300850V

PDBe

LIGANDS

Structure Chain	Target Protein	Gene	Expression System	Organism	Synonims	Actions
	P24941	TYMS, TS, OK/SW-CL.29	ESCHERICHIA COLI	HUMAN	TS, TSASE

NGL Viewer is used for the molecular visualization.

AS Rose, AR Bradley, Y Valasatava, JM Duarte, A Prlić and PW Rose. NGL viewer: web-based molecular graphics for large complexes. Bioinformatics: bty419, 2018. doi:10.1093/bioinformatics/bty419
AS Rose and PW Hildebrand. NGL Viewer: a web application for molecular visualization. Nucl Acids Res (1 July 2015) 43 (W1): W576-W579 first published online April 29, 2015. doi:10.1093/nar/gkv402