4F6S

3D Structure View

CAVITIES

STRUCTURE SETTINGS

LIGANDS

Bioassembly 4F6S_1

Chain 4F6S_A

Chain 4F6S_B

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GENERAL

TITLE

CRYSTAL STRUCTURE OF HUMAN CDK8/CYCC IN COMPLEX WITH COMPOUND 7 (1-[3- TERT-BUTYL-1-(4-METHYLPHENYL)-1H-PYRAZOL-5-YL]UREA)

DATE LAST MODIFIED

1 Apr 2015

RELEASE

1 May 2013

OBSOLETE

CLASSIFICATION

TRANSFERASE/TRANSCRIPTION/INHIBITOR

EXPERIMENT TYPE

X-RAY DIFFRACTION

SPACE GROUP

P 21 21 21

RESOLUTION RANGE HIGH

2.6

RESOLUTION RANGE LOW

85.86

PUBMED ID

DOI

10.1073/PNAS.1305378110

PDBe

LIGANDS

Structure Chain	Target Protein	Gene	Expression System	Organism	Synonims	Actions
	P49336	CDK8	SPODOPTERA FRUGIPERDA	HUMAN	CELL DIVISION PROTEIN KINASE 8, MEDIATOR COMPLEX S ...	Mutations
	P00648	CCNC	SPODOPTERA FRUGIPERDA	HUMAN	SRB11 HOMOLOG, HSRB11

NGL Viewer is used for the molecular visualization.

AS Rose, AR Bradley, Y Valasatava, JM Duarte, A Prlić and PW Rose. NGL viewer: web-based molecular graphics for large complexes. Bioinformatics: bty419, 2018. doi:10.1093/bioinformatics/bty419
AS Rose and PW Hildebrand. NGL Viewer: a web application for molecular visualization. Nucl Acids Res (1 July 2015) 43 (W1): W576-W579 first published online April 29, 2015. doi:10.1093/nar/gkv402