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GENERAL
TITLE
CRYSTAL STRUCTURE OF HUMAN CDK8/CYCC IN COMPLEX WITH COMPOUND 7 (1-[3- TERT-BUTYL-1-(4-METHYLPHENYL)-1H-PYRAZOL-5-YL]UREA)
DATE LAST MODIFIED
1 Apr 2015
RELEASE
1 May 2013
OBSOLETE
CLASSIFICATION
TRANSFERASE/TRANSCRIPTION/INHIBITOR
EXPERIMENT TYPE
X-RAY DIFFRACTION
SPACE GROUP
P 21 21 21
RESOLUTION RANGE HIGH
2.6
RESOLUTION RANGE LOW
85.86
PUBMED ID
DOI
10.1073/PNAS.1305378110
LIGANDS

Chains

Structure ChainTarget ProteinGeneExpression SystemOrganismSynonimsActions
P49336 CDK8 SPODOPTERA FRUGIPERDA HUMAN
CELL DIVISION PROTEIN KINASE 8, MEDIATOR COMPLEX S ...
Mutations
P24863 CCNC SPODOPTERA FRUGIPERDA HUMAN
SRB11 HOMOLOG, HSRB11
Mutations
NGL Viewer is used for the molecular visualization.
  • AS Rose, AR Bradley, Y Valasatava, JM Duarte, A Prlić and PW Rose. NGL viewer: web-based molecular graphics for large complexes. Bioinformatics: bty419, 2018. doi:10.1093/bioinformatics/bty419
  • AS Rose and PW Hildebrand. NGL Viewer: a web application for molecular visualization. Nucl Acids Res (1 July 2015) 43 (W1): W576-W579 first published online April 29, 2015. doi:10.1093/nar/gkv402