4FA6

3D Structure View

CAVITIES

STRUCTURE SETTINGS

LIGANDS

Chain 4FA6_A

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GENERAL

TITLE

DESIGN AND SYNTHESIS OF A NOVEL PYRROLIDINYL PYRIDO PYRIMIDINONE DERIVATIVE AS A POTENT INHIBITOR OF PI3KA AND MTOR

DATE LAST MODIFIED

RELEASE

3 Apr 2013

OBSOLETE

CLASSIFICATION

TRANSFERASE/TRANSFERASE INHIBITOR

EXPERIMENT TYPE

X-RAY DIFFRACTION

SPACE GROUP

C 1 2 1

RESOLUTION RANGE HIGH

2.7

RESOLUTION RANGE LOW

29.85

PUBMED ID

DOI

10.1016/J.BMCL.2012.05.100

PDBe

LIGANDS

Structure Chain	Target Protein	Gene	Expression System	Organism	Synonims	Actions
	P48736	PIK3CG	SPODOPTERA FRUGIPERDA	HUMAN	PI3-KINASE SUBUNIT GAMMA, PI3K-GAMMA, PI3KGAMMA, P ...	Mutations

NGL Viewer is used for the molecular visualization.

AS Rose, AR Bradley, Y Valasatava, JM Duarte, A Prlić and PW Rose. NGL viewer: web-based molecular graphics for large complexes. Bioinformatics: bty419, 2018. doi:10.1093/bioinformatics/bty419
AS Rose and PW Hildebrand. NGL Viewer: a web application for molecular visualization. Nucl Acids Res (1 July 2015) 43 (W1): W576-W579 first published online April 29, 2015. doi:10.1093/nar/gkv402