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GENERAL
TITLE
CRYSTAL STRUCTURE OF BETA-SITE APP-CLEAVING ENZYME 1 (BACE-DB-MUT) COMPLEX WITH N-(N-(4- ACETAMIDO-3-CHLORO-5-METHYLBENZYL) CARBAMIMIDOYL)-3-(4- METHOXYPHENYL)-5-METHYL-4-ISOTHIAZOLECARBOXAMIDE
DATE LAST MODIFIED
17 Jul 2019
RELEASE
10 Oct 2012
OBSOLETE
CLASSIFICATION
HYDROLASE/INHIBITOR
EXPERIMENT TYPE
X-RAY DIFFRACTION
SPACE GROUP
P 1 21 1
RESOLUTION RANGE HIGH
2.5
RESOLUTION RANGE LOW
50
PUBMED ID
DOI
10.1021/JM300931Y
PDBe
--
Chains
| Structure Chain | Target Protein | Gene | Expression System | Organism | Synonims | Actions |
|---|---|---|---|---|---|---|
| P05121 | BACE1, BACE, KIAA1149 | ESCHERICHIA COLI | HUMAN | ASPARTYL PROTEASE 2, ASP2, ASP 2, BETA-SITE AMYLOI ... | ||
| S4R2P9 | BACE1, BACE, KIAA1149 | ESCHERICHIA COLI | HUMAN | ASPARTYL PROTEASE 2, ASP2, ASP 2, BETA-SITE AMYLOI ... | ||
| P00750 | BACE1, BACE, KIAA1149 | ESCHERICHIA COLI | HUMAN | ASPARTYL PROTEASE 2, ASP2, ASP 2, BETA-SITE AMYLOI ... | ||
| P56817 | BACE1, BACE, KIAA1149 | ESCHERICHIA COLI | HUMAN | ASPARTYL PROTEASE 2, ASP2, ASP 2, BETA-SITE AMYLOI ... | Mutations |
NGL Viewer is used for the molecular visualization.
- AS Rose, AR Bradley, Y Valasatava, JM Duarte, A Prlić and PW Rose. NGL viewer: web-based molecular graphics for large complexes. Bioinformatics: bty419, 2018. doi:10.1093/bioinformatics/bty419
- AS Rose and PW Hildebrand. NGL Viewer: a web application for molecular visualization. Nucl Acids Res (1 July 2015) 43 (W1): W576-W579 first published online April 29, 2015. doi:10.1093/nar/gkv402