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GENERAL
TITLE
CRYSTAL STRUCTURE OF HUMAN TLR4 POLYMORPHIC VARIANT D299G AND T399I IN COMPLEX WITH MD-2 AND LPS
DATE LAST MODIFIED
29 Jul 2020
RELEASE
17 Oct 2012
OBSOLETE
CLASSIFICATION
IMMUNE SYSTEM
EXPERIMENT TYPE
X-RAY DIFFRACTION
SPACE GROUP
C 1 2 1
RESOLUTION RANGE HIGH
2.4
RESOLUTION RANGE LOW
39.2
PUBMED ID
DOI
10.1074/JBC.M112.404608
PDBe
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Chains

Structure ChainTarget ProteinGeneExpression SystemOrganismSynonimsActions
O00206 TLR4 DROSOPHILA HUMAN
HTOLL, PROTEIN TLR4
Mutations
O00206 TLR4 DROSOPHILA HUMAN
HTOLL, PROTEIN TLR4
Mutations
Q9Y6Y9 LY96, ESOP1, MD2 DROSOPHILA HUMAN
LY-96, ESOP-1, PROTEIN MD-2
Mutations
Q9Y6Y9 LY96, ESOP1, MD2 DROSOPHILA HUMAN
LY-96, ESOP-1, PROTEIN MD-2
Mutations
NGL Viewer is used for the molecular visualization.
  • AS Rose, AR Bradley, Y Valasatava, JM Duarte, A Prlić and PW Rose. NGL viewer: web-based molecular graphics for large complexes. Bioinformatics: bty419, 2018. doi:10.1093/bioinformatics/bty419
  • AS Rose and PW Hildebrand. NGL Viewer: a web application for molecular visualization. Nucl Acids Res (1 July 2015) 43 (W1): W576-W579 first published online April 29, 2015. doi:10.1093/nar/gkv402