4GU6

3D Structure View

CAVITIES

STRUCTURE SETTINGS

LIGANDS

Bioassembly 4GU6_1

Chain 4GU6_A

Chain 4GU6_B

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GENERAL

TITLE

FOCAL ADHESION KINASE CATALYTIC DOMAIN IN COMPLEX WITH N-{3-[(5-CYANO- 2-PHENYL-1H-PYRROLO[2,3-B]PYRIDIN-4-YLAMINO)- METHYL]-PYRIDIN-2-YL}- N-METHYL-METHANESULFONAMIDE

DATE LAST MODIFIED

RELEASE

4 Sept 2013

OBSOLETE

CLASSIFICATION

TRANSFERASE/TRANSFERASE INHIBITOR

EXPERIMENT TYPE

X-RAY DIFFRACTION

SPACE GROUP

P 21 21 21

RESOLUTION RANGE HIGH

1.95

RESOLUTION RANGE LOW

PUBMED ID

23294348

DOI

10.1021/JM3016014

PDBe

4GU6

LIGANDS

380999

Chains

Structure Chain	Target Protein	Gene	Expression System	Organism	Synonims	Actions
	P81947	PTK2, FAK, FAK1	TRICHOPLUSIA NI	HUMAN	FADK 1, FOCAL ADHESION KINASE-RELATED NONKINASE, F ...
	Q05397	PTK2, FAK, FAK1	TRICHOPLUSIA NI	HUMAN	FADK 1, FOCAL ADHESION KINASE-RELATED NONKINASE, F ...	Mutations

NGL Viewer is used for the molecular visualization.

AS Rose, AR Bradley, Y Valasatava, JM Duarte, A Prlić and PW Rose. NGL viewer: web-based molecular graphics for large complexes. Bioinformatics: bty419, 2018. doi:10.1093/bioinformatics/bty419
AS Rose and PW Hildebrand. NGL Viewer: a web application for molecular visualization. Nucl Acids Res (1 July 2015) 43 (W1): W576-W579 first published online April 29, 2015. doi:10.1093/nar/gkv402