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GENERAL
TITLE
FOCAL ADHESION KINASE CATALYTIC DOMAIN IN COMPLEX WITH N-{3-[(5-CYANO- 2-PHENYL-1H-PYRROLO[2,3-B]PYRIDIN-4-YLAMINO)- METHYL]-PYRIDIN-2-YL}- N-METHYL-METHANESULFONAMIDE
DATE LAST MODIFIED
-
RELEASE
4 Sept 2013
OBSOLETE
CLASSIFICATION
TRANSFERASE/TRANSFERASE INHIBITOR
EXPERIMENT TYPE
X-RAY DIFFRACTION
SPACE GROUP
P 21 21 21
RESOLUTION RANGE HIGH
1.95
RESOLUTION RANGE LOW
48
PUBMED ID
DOI
10.1021/JM3016014
LIGANDS

Chains

Structure ChainTarget ProteinGeneExpression SystemOrganismSynonimsActions
Q05397 PTK2, FAK, FAK1 TRICHOPLUSIA NI HUMAN
FADK 1, FOCAL ADHESION KINASE-RELATED NONKINASE, F ...
Mutations
Q05397 PTK2, FAK, FAK1 TRICHOPLUSIA NI HUMAN
FADK 1, FOCAL ADHESION KINASE-RELATED NONKINASE, F ...
Mutations
NGL Viewer is used for the molecular visualization.
  • AS Rose, AR Bradley, Y Valasatava, JM Duarte, A Prlić and PW Rose. NGL viewer: web-based molecular graphics for large complexes. Bioinformatics: bty419, 2018. doi:10.1093/bioinformatics/bty419
  • AS Rose and PW Hildebrand. NGL Viewer: a web application for molecular visualization. Nucl Acids Res (1 July 2015) 43 (W1): W576-W579 first published online April 29, 2015. doi:10.1093/nar/gkv402