4QT1

3D Structure View

CAVITIES

STRUCTURE SETTINGS

LIGANDS

Chain 4QT1_A

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GENERAL

TITLE

JAK3 KINASE DOMAIN IN COMPLEX WITH 1-[(3S)-1-ISOBUTYLSULFONYL-3- PIPERIDYL]-3-(5H-PYRROLO[2,3-B]PYRAZIN-2-YL)UREA

DATE LAST MODIFIED

RELEASE

27 May 2015

OBSOLETE

CLASSIFICATION

TRANSFERASE/TRANSFERASE INHIBITOR

EXPERIMENT TYPE

X-RAY DIFFRACTION

SPACE GROUP

P 21 21 21

RESOLUTION RANGE HIGH

2.4

RESOLUTION RANGE LOW

44.86

PUBMED ID

DOI

10.1016/J.BMCL.2014.09.031

PDBe

LIGANDS

Structure Chain	Target Protein	Gene	Expression System	Organism	Synonims	Actions
	P52333	JAK3	SPODOPTERA FRUGIPERDA	HUMAN	JANUS KINASE 3, JAK-3, LEUKOCYTE JANUS KINASE, L-J ...	Mutations

NGL Viewer is used for the molecular visualization.

AS Rose, AR Bradley, Y Valasatava, JM Duarte, A Prlić and PW Rose. NGL viewer: web-based molecular graphics for large complexes. Bioinformatics: bty419, 2018. doi:10.1093/bioinformatics/bty419
AS Rose and PW Hildebrand. NGL Viewer: a web application for molecular visualization. Nucl Acids Res (1 July 2015) 43 (W1): W576-W579 first published online April 29, 2015. doi:10.1093/nar/gkv402