4RN1

3D Structure View

CAVITIES

STRUCTURE SETTINGS

LIGANDS

Chain 4RN1_A

Chain 4RN1_B

Spin

Focus

Transparency

GENERAL

TITLE

CRYSTAL STRUCTURE OF S39D HDAC8 IN COMPLEX WITH A LARGAZOLE ANALOGUE.

DATE LAST MODIFIED

22 Apr 2015

RELEASE

8 Apr 2015

OBSOLETE

CLASSIFICATION

HYDROLASE/HYDROLASE INHIBITOR

EXPERIMENT TYPE

X-RAY DIFFRACTION

SPACE GROUP

P 1 21 1

RESOLUTION RANGE HIGH

2.18

RESOLUTION RANGE LOW

PUBMED ID

DOI

10.1021/ACS.BIOCHEM.5B00010

PDBe

LIGANDS

Structure Chain	Target Protein	Gene	Expression System	Organism	Synonims	Actions
	Q5JTV8	HDAC8, HDACL1, CDA07	ESCHERICHIA COLI	HUMAN	HD8
	Q9BY41	HDAC8, HDACL1, CDA07	ESCHERICHIA COLI	HUMAN	HD8	Mutations

NGL Viewer is used for the molecular visualization.

AS Rose, AR Bradley, Y Valasatava, JM Duarte, A Prlić and PW Rose. NGL viewer: web-based molecular graphics for large complexes. Bioinformatics: bty419, 2018. doi:10.1093/bioinformatics/bty419
AS Rose and PW Hildebrand. NGL Viewer: a web application for molecular visualization. Nucl Acids Res (1 July 2015) 43 (W1): W576-W579 first published online April 29, 2015. doi:10.1093/nar/gkv402