4UFZ

3D Structure View

CAVITIES

STRUCTURE SETTINGS

LIGANDS

Chain 4UFZ_A

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GENERAL

TITLE

SYNTHESIS OF NOVEL NAD DEPENDANT DNA LIGASE INHIBITORS VIA NEGISHI CROSS-COUPLING: DEVELOPMENT OF SAR AND RESISTANCE STUDIES

DATE LAST MODIFIED

4 Apr 2018

RELEASE

28 Oct 2015

OBSOLETE

CLASSIFICATION

LIGASE

EXPERIMENT TYPE

X-RAY DIFFRACTION

SPACE GROUP

P 43 21 2

RESOLUTION RANGE HIGH

2.33

RESOLUTION RANGE LOW

PUBMED ID

DOI

10.1016/J.BMCL.2015.09.075

PDBe

LIGANDS

Structure Chain	Target Protein	Gene	Expression System	Organism	Synonims	Actions
	P43813	--	ESCHERICHIA COLI	HAEMOPHILUS INFLUENZAE	POLYDEOXYRIBONUCLEOTIDE SYNTHASE NAD(+), NAD DEPEN ...	Mutations

NGL Viewer is used for the molecular visualization.

AS Rose, AR Bradley, Y Valasatava, JM Duarte, A Prlić and PW Rose. NGL viewer: web-based molecular graphics for large complexes. Bioinformatics: bty419, 2018. doi:10.1093/bioinformatics/bty419
AS Rose and PW Hildebrand. NGL Viewer: a web application for molecular visualization. Nucl Acids Res (1 July 2015) 43 (W1): W576-W579 first published online April 29, 2015. doi:10.1093/nar/gkv402