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GENERAL
TITLE
CRYSTAL STRUCTURE OF THE FIRST BROMODOMAIN OF HUMAN BRD4 IN COMPLEX WITH A NOVEL INHIBITOR UMB32 (N-TERT-BUTYL-2-[4-(3,5-DIMETHYL-1,2- OXAZOL-4-YL) PHENYL]IMIDAZO[1,2-A]PYRAZIN-3-AMINE)
DATE LAST MODIFIED
26 Aug 2015
RELEASE
29 Oct 2014
OBSOLETE
CLASSIFICATION
TRANSCRIPTION/TRANSCRIPTION INHIBITOR
EXPERIMENT TYPE
X-RAY DIFFRACTION
SPACE GROUP
P 21 21 21
RESOLUTION RANGE HIGH
1.56
RESOLUTION RANGE LOW
35.45
PUBMED ID
DOI
10.1021/JM501120Z
PDBe
4WIV
Chains
| Structure Chain | Target Protein | Gene | Expression System | Organism | Synonims | Actions |
|---|---|---|---|---|---|---|
| Q6B0I6 | BRD4, HUNK1 | ESCHERICHIA COLI | HUMAN | PROTEIN HUNK1 |
NGL Viewer is used for the molecular visualization.
- AS Rose, AR Bradley, Y Valasatava, JM Duarte, A Prlić and PW Rose. NGL viewer: web-based molecular graphics for large complexes. Bioinformatics: bty419, 2018. doi:10.1093/bioinformatics/bty419
- AS Rose and PW Hildebrand. NGL Viewer: a web application for molecular visualization. Nucl Acids Res (1 July 2015) 43 (W1): W576-W579 first published online April 29, 2015. doi:10.1093/nar/gkv402