4X2G

3D Structure View

CAVITIES

STRUCTURE SETTINGS

LIGANDS

Chain 4X2G_A

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GENERAL

TITLE

SELECTION OF FRAGMENTS FOR KINASE INHIBITOR DESIGN: DECORATION IS KEY

DATE LAST MODIFIED

RELEASE

12 Aug 2015

OBSOLETE

CLASSIFICATION

TRANSFERASE/TRANSFERASE INHIBITOR

EXPERIMENT TYPE

X-RAY DIFFRACTION

SPACE GROUP

P 21 21 21

RESOLUTION RANGE HIGH

1.51

RESOLUTION RANGE LOW

22.11

PUBMED ID

DOI

10.1021/JM501597J

PDBe

LIGANDS

Structure Chain	Target Protein	Gene	Expression System	Organism	Synonims	Actions
	P0C6X7-Nsp13	TGFBR1, ALK5, SKR4	SPODOPTERA FRUGIPERDA	HUMAN	TGFR-1,ACTIVIN A RECEPTOR TYPE II-LIKE PROTEIN KIN ...

NGL Viewer is used for the molecular visualization.

AS Rose, AR Bradley, Y Valasatava, JM Duarte, A Prlić and PW Rose. NGL viewer: web-based molecular graphics for large complexes. Bioinformatics: bty419, 2018. doi:10.1093/bioinformatics/bty419
AS Rose and PW Hildebrand. NGL Viewer: a web application for molecular visualization. Nucl Acids Res (1 July 2015) 43 (W1): W576-W579 first published online April 29, 2015. doi:10.1093/nar/gkv402