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GENERAL
TITLE
CO-CRYSTAL STRUCTURE OF PERK BOUND TO N-{5-[(6,7-DIMETHOXYQUINOLIN-4- YL)OXY]PYRIDIN-2-YL}-1-METHYL-3-OXO-2-PHENYL-5-(PYRIDIN-4-YL)-2,3- DIHYDRO-1H-PYRAZOLE-4-CARBOXAMIDE INHIBITOR
DATE LAST MODIFIED
22 Nov 2017
RELEASE
4 Feb 2015
OBSOLETE
CLASSIFICATION
TRANSFERASE/TRANSFERASE INHIBITOR
EXPERIMENT TYPE
X-RAY DIFFRACTION
SPACE GROUP
P 41 21 2
RESOLUTION RANGE HIGH
2
RESOLUTION RANGE LOW
50
PUBMED ID
DOI
10.1021/JM5017494
PDBe
4X7H
Chains
| Structure Chain | Target Protein | Gene | Expression System | Organism | Synonims | Actions |
|---|---|---|---|---|---|---|
| Q5R3K3 | EIF2AK3, PEK, PERK | ESCHERICHIA COLI | HUMAN | PRKR-LIKE ENDOPLASMIC RETICULUM KINASE,PANCREATIC ... |
NGL Viewer is used for the molecular visualization.
- AS Rose, AR Bradley, Y Valasatava, JM Duarte, A Prlić and PW Rose. NGL viewer: web-based molecular graphics for large complexes. Bioinformatics: bty419, 2018. doi:10.1093/bioinformatics/bty419
- AS Rose and PW Hildebrand. NGL Viewer: a web application for molecular visualization. Nucl Acids Res (1 July 2015) 43 (W1): W576-W579 first published online April 29, 2015. doi:10.1093/nar/gkv402