5AAB

3D Structure View

CAVITIES

STRUCTURE SETTINGS

LIGANDS

Chain 5AAB_A

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GENERAL

TITLE

STRUCTURE OF C1156Y,L1198F MUTANT HUMAN ANAPLASTIC LYMPHOMA KINASE IN COMPLEX WITH CRIZOTINIB

DATE LAST MODIFIED

8 May 2019

RELEASE

8 Jun 2016

OBSOLETE

CLASSIFICATION

TRANSFERASE

EXPERIMENT TYPE

X-RAY DIFFRACTION

SPACE GROUP

P 21 21 21

RESOLUTION RANGE HIGH

2.2

RESOLUTION RANGE LOW

104.7

PUBMED ID

DOI

10.1056/NEJMOA1508887

PDBe

LIGANDS

Structure Chain	Target Protein	Gene	Expression System	Organism	Synonims	Actions
	Q9UM73	--	SPODOPTERA FRUGIPERDA	HUMAN	ANAPLASTIC LYMPHOMA KINASE	Mutations

NGL Viewer is used for the molecular visualization.

AS Rose, AR Bradley, Y Valasatava, JM Duarte, A Prlić and PW Rose. NGL viewer: web-based molecular graphics for large complexes. Bioinformatics: bty419, 2018. doi:10.1093/bioinformatics/bty419
AS Rose and PW Hildebrand. NGL Viewer: a web application for molecular visualization. Nucl Acids Res (1 July 2015) 43 (W1): W576-W579 first published online April 29, 2015. doi:10.1093/nar/gkv402