5GPG

3D Structure View

CAVITIES

STRUCTURE SETTINGS

LIGANDS

Bioassembly 5GPG_1

Chain 5GPG_A

Chain 5GPG_B

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GENERAL

TITLE

CO-CRYSTAL STRUCTURE OF THE FK506 BINDING DOMAIN OF HUMAN FKBP25, RAPAMYCIN AND THE FRB DOMAIN OF HUMAN MTOR

DATE LAST MODIFIED

RELEASE

12 Oct 2016

OBSOLETE

CLASSIFICATION

ISOMERASE/TRANSFERASE

EXPERIMENT TYPE

X-RAY DIFFRACTION

SPACE GROUP

P 21 21 21

RESOLUTION RANGE HIGH

1.669

RESOLUTION RANGE LOW

PUBMED ID

DOI

10.1021/ACSCENTSCI.6B00137

PDBe

LIGANDS

Structure Chain	Target Protein	Gene	Expression System	Organism	Synonims	Actions
	Q00688	FKBP3, FKBP25	ESCHERICHIA COLI BL21(DE3)	HUMAN	PPIASE FKBP3,25 KDA FK506-BINDING PROTEIN,FKBP-25, ...	Mutations
	D2YW39	MTOR, FRAP, FRAP1, FRAP2, RAFT1, RAPT1	ESCHERICHIA COLI BL21(DE3)	HUMAN	FK506-BINDING PROTEIN 12-RAPAMYCIN COMPLEX-ASSOCIA ...

NGL Viewer is used for the molecular visualization.

AS Rose, AR Bradley, Y Valasatava, JM Duarte, A Prlić and PW Rose. NGL viewer: web-based molecular graphics for large complexes. Bioinformatics: bty419, 2018. doi:10.1093/bioinformatics/bty419
AS Rose and PW Hildebrand. NGL Viewer: a web application for molecular visualization. Nucl Acids Res (1 July 2015) 43 (W1): W576-W579 first published online April 29, 2015. doi:10.1093/nar/gkv402