3D Structure View
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GENERAL
TITLE
HUMAN TOPOISOMERASE IIALPHA IN COMPLEX WITH DNA AND ETOPOSIDE
DATE LAST MODIFIED
8 Nov 2017
RELEASE
23 Aug 2017
OBSOLETE
CLASSIFICATION
ISOMERASE/DNA/ISOMERASE INHIBITOR
EXPERIMENT TYPE
X-RAY DIFFRACTION
SPACE GROUP
P 21 2 21
RESOLUTION RANGE HIGH
3.15
RESOLUTION RANGE LOW
27.49
PUBMED ID
DOI
10.1093/NAR/GKX742
PDBe
5GWK
Chains
| Structure Chain | Target Protein | Gene | Expression System | Organism | Synonims | Actions |
|---|---|---|---|---|---|---|
| P11388 | TOP2A, TOP2 | ESCHERICHIA COLI BL21(DE3) | HUMAN | DNA TOPOISOMERASE II,ALPHA ISOZYME | Mutations | |
| P11388 | TOP2A, TOP2 | ESCHERICHIA COLI BL21(DE3) | HUMAN | DNA TOPOISOMERASE II,ALPHA ISOZYME | Mutations | |
| -- | -- | SYNTHETIC CONSTRUCT | -- | |||
| P35523 | -- | -- | SYNTHETIC CONSTRUCT | -- | ||
| -- | -- | SYNTHETIC CONSTRUCT | -- | |||
| P35523 | -- | -- | SYNTHETIC CONSTRUCT | -- |
NGL Viewer is used for the molecular visualization.
- AS Rose, AR Bradley, Y Valasatava, JM Duarte, A Prlić and PW Rose. NGL viewer: web-based molecular graphics for large complexes. Bioinformatics: bty419, 2018. doi:10.1093/bioinformatics/bty419
- AS Rose and PW Hildebrand. NGL Viewer: a web application for molecular visualization. Nucl Acids Res (1 July 2015) 43 (W1): W576-W579 first published online April 29, 2015. doi:10.1093/nar/gkv402