5HE5

3D Structure View

CAVITIES

STRUCTURE SETTINGS

LIGANDS

Chain 5HE5_A

Chain 5HE5_B

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GENERAL

TITLE

BACE-1 IN COMPLEX WITH (7AR)-7A-(5-CYANOTHIOPHEN-2-YL)-6-(5-FLUORO-4- METHYL-6-(METHYLAMINO)PYRIMIDIN-2-YL)-3-METHYL-4-OXOOCTAHYDRO-2H- PYRROLO[3,4-D]PYRIMIDIN-2-IMINIUM

DATE LAST MODIFIED

27 Apr 2016

RELEASE

16 Mar 2016

OBSOLETE

CLASSIFICATION

HYDROLASE/HYDROLASE INHIBITOR

EXPERIMENT TYPE

X-RAY DIFFRACTION

SPACE GROUP

P 21 21 21

RESOLUTION RANGE HIGH

1.55

RESOLUTION RANGE LOW

PUBMED ID

26937601

DOI

10.1021/ACS.JMEDCHEM.5B01995

PDBe

5HE5

LIGANDS

220524 , 67113

Chains

Structure Chain	Target Protein	Gene	Expression System	Organism	Synonims	Actions
	Q9Y5W9	BACE1, BACE, KIAA1149	ESCHERICHIA COLI	HUMAN	ASPARTYL PROTEASE 2,ASP 2,BETA-SITE AMYLOID PRECUR ...
	Q9Y5W9	BACE1, BACE, KIAA1149	ESCHERICHIA COLI	HUMAN	ASPARTYL PROTEASE 2,ASP 2,BETA-SITE AMYLOID PRECUR ...

NGL Viewer is used for the molecular visualization.

AS Rose, AR Bradley, Y Valasatava, JM Duarte, A Prlić and PW Rose. NGL viewer: web-based molecular graphics for large complexes. Bioinformatics: bty419, 2018. doi:10.1093/bioinformatics/bty419
AS Rose and PW Hildebrand. NGL Viewer: a web application for molecular visualization. Nucl Acids Res (1 July 2015) 43 (W1): W576-W579 first published online April 29, 2015. doi:10.1093/nar/gkv402