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GENERAL
TITLE
HUMAN CYTOCHROME P450 17A1 BOUND TO INHIBITORS (R)- AND (S)- ORTERONEL
DATE LAST MODIFIED
25 Dec 2019
RELEASE
15 Mar 2017
OBSOLETE
CLASSIFICATION
OXIDOREDUCTASE, LYASE/INHIBITOR
EXPERIMENT TYPE
X-RAY DIFFRACTION
SPACE GROUP
P 21 21 21
RESOLUTION RANGE HIGH
2.2
RESOLUTION RANGE LOW
39.29
PUBMED ID
DOI
10.1124/DMD.117.075317
PDBe
5IRQ
Chains
| Structure Chain | Target Protein | Gene | Expression System | Organism | Synonims | Actions |
|---|---|---|---|---|---|---|
| Q12046 | CYP17A1, CYP17, S17AH | ESCHERICHIA COLI | HUMAN | 17-ALPHA-HYDROXYPROGESTERONE ALDOLASE, CYPXVII, CY ... | ||
| P53854 | CYP17A1, CYP17, S17AH | ESCHERICHIA COLI | HUMAN | 17-ALPHA-HYDROXYPROGESTERONE ALDOLASE, CYPXVII, CY ... | ||
| P25337 | CYP17A1, CYP17, S17AH | ESCHERICHIA COLI | HUMAN | 17-ALPHA-HYDROXYPROGESTERONE ALDOLASE, CYPXVII, CY ... | ||
| Q12309 | CYP17A1, CYP17, S17AH | ESCHERICHIA COLI | HUMAN | 17-ALPHA-HYDROXYPROGESTERONE ALDOLASE, CYPXVII, CY ... |
NGL Viewer is used for the molecular visualization.
- AS Rose, AR Bradley, Y Valasatava, JM Duarte, A Prlić and PW Rose. NGL viewer: web-based molecular graphics for large complexes. Bioinformatics: bty419, 2018. doi:10.1093/bioinformatics/bty419
- AS Rose and PW Hildebrand. NGL Viewer: a web application for molecular visualization. Nucl Acids Res (1 July 2015) 43 (W1): W576-W579 first published online April 29, 2015. doi:10.1093/nar/gkv402