5ISO

3D Structure View

CAVITIES

STRUCTURE SETTINGS

LIGANDS

Bioassembly 5ISO_1

Bioassembly 5ISO_2

Chain 5ISO_A

Chain 5ISO_B

Chain 5ISO_C

Chain 5ISO_D

Chain 5ISO_E

Chain 5ISO_F

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GENERAL

TITLE

STRUCTURE OF FULL LENGTH HUMAN AMPK (NON-PHOSPHORYLATED AT T-LOOP) IN COMPLEX WITH A SMALL MOLECULE ACTIVATOR, A BENZIMIDAZOLE DERIVATIVE (991)

DATE LAST MODIFIED

16 Oct 2019

RELEASE

29 Mar 2017

OBSOLETE

CLASSIFICATION

TRANSFERASE

EXPERIMENT TYPE

X-RAY DIFFRACTION

SPACE GROUP

P 1 21 1

RESOLUTION RANGE HIGH

2.63

RESOLUTION RANGE LOW

47.37

PUBMED ID

DOI

PDBe

LIGANDS

Target Protein	Gene	Expression System	Organism	Synonims	Actions
P54646	PRKAA2, AMPK, AMPK2	ESCHERICHIA COLI	HUMAN	AMPK SUBUNIT ALPHA-2,ACETYL-COA CARBOXYLASE KINASE ...	Mutations
P38968	PRKAB1, AMPK	ESCHERICHIA COLI	HUMAN	AMPKB16 RESIDUES (MGLNDIFEAQKIEWHE) AT THE N-TERMI ...
P54646	PRKAA2, AMPK, AMPK2	ESCHERICHIA COLI	HUMAN	AMPK SUBUNIT ALPHA-2,ACETYL-COA CARBOXYLASE KINASE ...	Mutations
P38968	PRKAB1, AMPK	ESCHERICHIA COLI	HUMAN	AMPKB16 RESIDUES (MGLNDIFEAQKIEWHE) AT THE N-TERMI ...
P54619	PRKAG1	ESCHERICHIA COLI	HUMAN	AMPKG	Mutations
P54619	PRKAG1	ESCHERICHIA COLI	HUMAN	AMPKG	Mutations

NGL Viewer is used for the molecular visualization.

AS Rose, AR Bradley, Y Valasatava, JM Duarte, A Prlić and PW Rose. NGL viewer: web-based molecular graphics for large complexes. Bioinformatics: bty419, 2018. doi:10.1093/bioinformatics/bty419
AS Rose and PW Hildebrand. NGL Viewer: a web application for molecular visualization. Nucl Acids Res (1 July 2015) 43 (W1): W576-W579 first published online April 29, 2015. doi:10.1093/nar/gkv402