5IW0

3D Structure View

CAVITIES

STRUCTURE SETTINGS

LIGANDS

Chain 5IW0_A

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GENERAL

TITLE

LINKED KDM5A JMJ DOMAIN BOUND TO THE INHIBITOR N19 [2-(5-((4-CHLORO-2- METHYLBENZYL)OXY)-1H-PYRAZOL-1-YL)ISONICOTINIC ACID]

DATE LAST MODIFIED

3 Aug 2016

RELEASE

27 Jul 2016

OBSOLETE

CLASSIFICATION

OXIDOREDUCTASE/OXIDOREDUCTASE INHIBITOR

EXPERIMENT TYPE

X-RAY DIFFRACTION

SPACE GROUP

C 1 2 1

RESOLUTION RANGE HIGH

1.63

RESOLUTION RANGE LOW

32.97

PUBMED ID

DOI

10.1016/J.CHEMBIOL.2016.06.006

PDBe

LIGANDS

Structure Chain	Target Protein	Gene	Expression System	Organism	Synonims	Actions
	P29375	KDM5A, JARID1A, RBBP2, RBP2	ESCHERICHIA COLI	HUMAN	ISTONE DEMETHYLASE JARID1A,JUMONJI/ARID DOMAIN-CON ...	Mutations

NGL Viewer is used for the molecular visualization.

AS Rose, AR Bradley, Y Valasatava, JM Duarte, A Prlić and PW Rose. NGL viewer: web-based molecular graphics for large complexes. Bioinformatics: bty419, 2018. doi:10.1093/bioinformatics/bty419
AS Rose and PW Hildebrand. NGL Viewer: a web application for molecular visualization. Nucl Acids Res (1 July 2015) 43 (W1): W576-W579 first published online April 29, 2015. doi:10.1093/nar/gkv402