5J6D

3D Structure View

CAVITIES

STRUCTURE SETTINGS

LIGANDS

Bioassembly 5J6D_3

Chain 5J6D_A

Chain 5J6D_B

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GENERAL

TITLE

DISCOVERY OF ACYL GUANIDINE TRYPTOPHAN HYDROXYLASE-1 INHIBITORS

DATE LAST MODIFIED

15 Jun 2016

RELEASE

25 May 2016

OBSOLETE

CLASSIFICATION

OXIDOREDUCTASE/INHIBITOR

EXPERIMENT TYPE

X-RAY DIFFRACTION

SPACE GROUP

P 21 21 21

RESOLUTION RANGE HIGH

1.9

RESOLUTION RANGE LOW

PUBMED ID

DOI

10.1016/J.BMCL.2016.04.057

PDBe

LIGANDS

Structure Chain	Target Protein	Gene	Expression System	Organism	Synonims	Actions
	Q8TCE9	TPH1, TPH, TPRH, TRPH	ESCHERICHIA COLI	HUMAN	TRYPTOPHAN 5-MONOOXYGENASE 1
	Q8TCE9	TPH1, TPH, TPRH, TRPH	ESCHERICHIA COLI	HUMAN	TRYPTOPHAN 5-MONOOXYGENASE 1

NGL Viewer is used for the molecular visualization.

AS Rose, AR Bradley, Y Valasatava, JM Duarte, A Prlić and PW Rose. NGL viewer: web-based molecular graphics for large complexes. Bioinformatics: bty419, 2018. doi:10.1093/bioinformatics/bty419
AS Rose and PW Hildebrand. NGL Viewer: a web application for molecular visualization. Nucl Acids Res (1 July 2015) 43 (W1): W576-W579 first published online April 29, 2015. doi:10.1093/nar/gkv402