5J7G

3D Structure View

CAVITIES

STRUCTURE SETTINGS

LIGANDS

Bioassembly 5J7G_1

Bioassembly 5J7G_2

Bioassembly 5J7G_3

Chain 5J7G_A

Chain 5J7G_B

Chain 5J7G_C

Chain 5J7G_D

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GENERAL

TITLE

STRUCTURE OF MDM2 WITH LOW MOLECULAR WEIGHT INHIBITOR WITH ALIPHATIC LINKER.

DATE LAST MODIFIED

31 Jan 2018

RELEASE

17 May 2017

OBSOLETE

CLASSIFICATION

LIGASE

EXPERIMENT TYPE

X-RAY DIFFRACTION

SPACE GROUP

P 2 21 21

RESOLUTION RANGE HIGH

1.85

RESOLUTION RANGE LOW

85.7

PUBMED ID

DOI

10.1021/ACS.JMEDCHEM.7B00104

PDBe

LIGANDS

Target Protein	Gene	Expression System	Organism	Synonims	Actions
P62799	MDM2	ESCHERICHIA COLI	HUMAN	DOUBLE MINUTE 2 PROTEIN,HDM2,ONCOPROTEIN MDM2,P53- ...
P33334	MDM2	ESCHERICHIA COLI	HUMAN	DOUBLE MINUTE 2 PROTEIN,HDM2,ONCOPROTEIN MDM2,P53- ...
P62799	MDM2	ESCHERICHIA COLI	HUMAN	DOUBLE MINUTE 2 PROTEIN,HDM2,ONCOPROTEIN MDM2,P53- ...
Q00987	MDM2	ESCHERICHIA COLI	HUMAN	DOUBLE MINUTE 2 PROTEIN,HDM2,ONCOPROTEIN MDM2,P53- ...	Mutations

NGL Viewer is used for the molecular visualization.

AS Rose, AR Bradley, Y Valasatava, JM Duarte, A Prlić and PW Rose. NGL viewer: web-based molecular graphics for large complexes. Bioinformatics: bty419, 2018. doi:10.1093/bioinformatics/bty419
AS Rose and PW Hildebrand. NGL Viewer: a web application for molecular visualization. Nucl Acids Res (1 July 2015) 43 (W1): W576-W579 first published online April 29, 2015. doi:10.1093/nar/gkv402