5KVT

3D Structure View

CAVITIES

STRUCTURE SETTINGS

LIGANDS

Chain 5KVT_A

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GENERAL

TITLE

THE STRUCTURE OF TRKA KINASE DOMAIN BOUND TO THE INHIBITOR ENTRECTINIB

DATE LAST MODIFIED

RELEASE

27 Dec 2017

OBSOLETE

CLASSIFICATION

TRANSFERASE/TRANSFERASE INHIBITOR

EXPERIMENT TYPE

X-RAY DIFFRACTION

SPACE GROUP

P 64

RESOLUTION RANGE HIGH

2.45

RESOLUTION RANGE LOW

65.73

PUBMED ID

DOI

PDBe

LIGANDS

Structure Chain	Target Protein	Gene	Expression System	Organism	Synonims	Actions
	P04629	NTRK1, MTC, TRK, TRKA	SPODOPTERA FRUGIPERDA	HUMAN	NEUROTROPHIC TYROSINE KINASE RECEPTOR TYPE 1,TRK1- ...	Mutations

NGL Viewer is used for the molecular visualization.

AS Rose, AR Bradley, Y Valasatava, JM Duarte, A Prlić and PW Rose. NGL viewer: web-based molecular graphics for large complexes. Bioinformatics: bty419, 2018. doi:10.1093/bioinformatics/bty419
AS Rose and PW Hildebrand. NGL Viewer: a web application for molecular visualization. Nucl Acids Res (1 July 2015) 43 (W1): W576-W579 first published online April 29, 2015. doi:10.1093/nar/gkv402