5LAW

3D Structure View

CAVITIES

STRUCTURE SETTINGS

LIGANDS

Chain 5LAW_A

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GENERAL

TITLE

NOVEL SPIRO[3H-INDOLE-3,2 -PYRROLIDIN]-2(1H)-ONE INHIBITORS OF THE MDM2-P53 INTERACTION: HDM2 (MDM2) IN COMPLEX WITH COMPOUND 14

DATE LAST MODIFIED

25 Sept 2019

RELEASE

2 Nov 2016

OBSOLETE

CLASSIFICATION

LIGASE

EXPERIMENT TYPE

X-RAY DIFFRACTION

SPACE GROUP

P 61 2 2

RESOLUTION RANGE HIGH

1.64

RESOLUTION RANGE LOW

48.68

PUBMED ID

DOI

10.1021/ACS.JMEDCHEM.6B00900

PDBe

LIGANDS

Structure Chain	Target Protein	Gene	Expression System	Organism	Synonims	Actions
	O95696	--	--	HUMAN	DOUBLE MINUTE 2 PROTEIN,HDM2,ONCOPROTEIN MDM2,P53- ...

NGL Viewer is used for the molecular visualization.

AS Rose, AR Bradley, Y Valasatava, JM Duarte, A Prlić and PW Rose. NGL viewer: web-based molecular graphics for large complexes. Bioinformatics: bty419, 2018. doi:10.1093/bioinformatics/bty419
AS Rose and PW Hildebrand. NGL Viewer: a web application for molecular visualization. Nucl Acids Res (1 July 2015) 43 (W1): W576-W579 first published online April 29, 2015. doi:10.1093/nar/gkv402