5LGU

3D Structure View

CAVITIES

STRUCTURE SETTINGS

LIGANDS

Bioassembly 5LGU_1

Chain 5LGU_A

Chain 5LGU_B

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GENERAL

TITLE

THIENO[3,2-B]PYRROLE-5-CARBOXAMIDES AS NOVEL REVERSIBLE INHIBITORS OF HISTONE LYSINE DEMETHYLASE KDM1A/LSD1: COMPOUND 34

DATE LAST MODIFIED

22 Mar 2017

RELEASE

22 Feb 2017

OBSOLETE

CLASSIFICATION

OXIDOREDUCTASE

EXPERIMENT TYPE

X-RAY DIFFRACTION

SPACE GROUP

I 2 2 2

RESOLUTION RANGE HIGH

3.2

RESOLUTION RANGE LOW

PUBMED ID

DOI

10.1021/ACS.JMEDCHEM.6B01019

PDBe

LIGANDS

Structure Chain	Target Protein	Gene	Expression System	Organism	Synonims	Actions
	P04390	KDM1A, AOF2, KDM1, KIAA0601, LSD1	ESCHERICHIA COLI	HUMAN	BRAF35-HDAC COMPLEX PROTEIN BHC110,FLAVIN-CONTAINI ...
	P04390	RCOR1, KIAA0071, RCOR	ESCHERICHIA COLI	HUMAN	PROTEIN COREST

NGL Viewer is used for the molecular visualization.

AS Rose, AR Bradley, Y Valasatava, JM Duarte, A Prlić and PW Rose. NGL viewer: web-based molecular graphics for large complexes. Bioinformatics: bty419, 2018. doi:10.1093/bioinformatics/bty419
AS Rose and PW Hildebrand. NGL Viewer: a web application for molecular visualization. Nucl Acids Res (1 July 2015) 43 (W1): W576-W579 first published online April 29, 2015. doi:10.1093/nar/gkv402