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GENERAL
TITLE
CRYSTAL STRUCTURE OF HUMAN AKR1B10 COMPLEXED WITH NADP+ AND THE INHIBITOR MK184
DATE LAST MODIFIED
2 Nov 2016
RELEASE
27 Jul 2016
OBSOLETE
CLASSIFICATION
OXIDOREDUCTASE
EXPERIMENT TYPE
X-RAY DIFFRACTION
SPACE GROUP
P 31
RESOLUTION RANGE HIGH
1.95
RESOLUTION RANGE LOW
50
PUBMED ID
DOI
10.1021/ACSCHEMBIO.6B00382
PDBe
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Chains

Structure ChainTarget ProteinGeneExpression SystemOrganismSynonymsActions
O60218 AKR1B10, AKR1B11 ESCHERICHIA COLI HUMAN ARL-1,ALDOSE REDUCTASE-LIKE,ALDOSE REDUCTASE-RELATEDPROTEIN,HARP,SMALL INTESTINE REDUCTASE,SI REDUCTASE HUMAN
ARL-1,ALDOSE REDUCTASE-LIKE,ALDOSE REDUCTASE-RELAT ...
Mutations
NGL Viewer is used for the molecular visualization.
  • AS Rose, AR Bradley, Y Valasatava, JM Duarte, A Prlić and PW Rose. NGL viewer: web-based molecular graphics for large complexes. Bioinformatics: bty419, 2018. doi:10.1093/bioinformatics/bty419
  • AS Rose and PW Hildebrand. NGL Viewer: a web application for molecular visualization. Nucl Acids Res (1 July 2015) 43 (W1): W576-W579 first published online April 29, 2015. doi:10.1093/nar/gkv402