5LN2

3D Structure View

CAVITIES

STRUCTURE SETTINGS

LIGANDS

Chain 5LN2_A

Spin

Focus

Transparency

GENERAL

TITLE

DISCOVERY OF A NOVEL CLASS OF HIGHLY POTENT INHIBITORS OF THE P53-MDM2 INTERACTION BY STRUCTURE-BASED DESIGN STARTING FROM A CONFORMATIONAL ARGUMENT

DATE LAST MODIFIED

21 Sept 2016

RELEASE

7 Sept 2016

OBSOLETE

CLASSIFICATION

CELL CYCLE

EXPERIMENT TYPE

X-RAY DIFFRACTION

SPACE GROUP

P 61 2 2

RESOLUTION RANGE HIGH

1.58

RESOLUTION RANGE LOW

PUBMED ID

DOI

10.1016/J.BMCL.2016.08.010

PDBe

LIGANDS

Structure Chain	Target Protein	Gene	Expression System	Organism	Synonims	Actions
	Q00987	MDM2	ESCHERICHIA COLI	HUMAN	DOUBLE MINUTE 2 PROTEIN,HDM2,ONCOPROTEIN MDM2,P53- ...	Mutations

NGL Viewer is used for the molecular visualization.

AS Rose, AR Bradley, Y Valasatava, JM Duarte, A Prlić and PW Rose. NGL viewer: web-based molecular graphics for large complexes. Bioinformatics: bty419, 2018. doi:10.1093/bioinformatics/bty419
AS Rose and PW Hildebrand. NGL Viewer: a web application for molecular visualization. Nucl Acids Res (1 July 2015) 43 (W1): W576-W579 first published online April 29, 2015. doi:10.1093/nar/gkv402