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GENERAL
TITLE
STRUCTURE OF THE EPIGENETIC ONCOGENE MMSET AND INHIBITION BY N-ALKYL SINEFUNGIN DERIVATIVES
DATE LAST MODIFIED
21 Dec 2016
RELEASE
5 Oct 2016
OBSOLETE
CLASSIFICATION
TRANSFERASE
EXPERIMENT TYPE
X-RAY DIFFRACTION
SPACE GROUP
P 21 21 21
RESOLUTION RANGE HIGH
2.14
RESOLUTION RANGE LOW
61.56
PUBMED ID
DOI
10.1021/ACSCHEMBIO.6B00308
LIGANDS

Chains

Structure ChainTarget ProteinGeneExpression SystemOrganismSynonimsActions
O96028 WHSC1, KIAA1090, MMSET, NSD2, TRX5 ESCHERICHIA COLI HUMAN
MULTIPLE MYELOMA SET DOMAIN-CONTAINING PROTEIN,MMS ...
Mutations
O96028 WHSC1, KIAA1090, MMSET, NSD2, TRX5 ESCHERICHIA COLI HUMAN
MULTIPLE MYELOMA SET DOMAIN-CONTAINING PROTEIN,MMS ...
Mutations
NGL Viewer is used for the molecular visualization.
  • AS Rose, AR Bradley, Y Valasatava, JM Duarte, A Prlić and PW Rose. NGL viewer: web-based molecular graphics for large complexes. Bioinformatics: bty419, 2018. doi:10.1093/bioinformatics/bty419
  • AS Rose and PW Hildebrand. NGL Viewer: a web application for molecular visualization. Nucl Acids Res (1 July 2015) 43 (W1): W576-W579 first published online April 29, 2015. doi:10.1093/nar/gkv402