5MWJ

3D Structure View

CAVITIES

STRUCTURE SETTINGS

LIGANDS

Bioassembly 5MWJ_1

Chain 5MWJ_A

Chain 5MWJ_B

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GENERAL

TITLE

STRUCTURE ENABLED DISCOVERY OF A STAPLED PEPTIDE INHIBITOR TO TARGET THE ONCOGENIC TRANSCRIPTIONAL REPRESSOR TLE1

DATE LAST MODIFIED

16 Oct 2019

RELEASE

5 Apr 2017

OBSOLETE

CLASSIFICATION

TRANSCRIPTION

EXPERIMENT TYPE

X-RAY DIFFRACTION

SPACE GROUP

P 1 21 1

RESOLUTION RANGE HIGH

2.04

RESOLUTION RANGE LOW

PUBMED ID

DOI

10.1002/CHEM.201700747

PDBe

LIGANDS

Structure Chain	Target Protein	Gene	Expression System	Organism	Synonims	Actions
	P19052	TLE1	SPODOPTERA FRUGIPERDA	HUMAN	E(SP1) HOMOLOG,ENHANCER OF SPLIT GROUCHO-LIKE PROT ...
	D0VWR1	TLE1	SPODOPTERA FRUGIPERDA	HUMAN	E(SP1) HOMOLOG,ENHANCER OF SPLIT GROUCHO-LIKE PROT ...

NGL Viewer is used for the molecular visualization.

AS Rose, AR Bradley, Y Valasatava, JM Duarte, A Prlić and PW Rose. NGL viewer: web-based molecular graphics for large complexes. Bioinformatics: bty419, 2018. doi:10.1093/bioinformatics/bty419
AS Rose and PW Hildebrand. NGL Viewer: a web application for molecular visualization. Nucl Acids Res (1 July 2015) 43 (W1): W576-W579 first published online April 29, 2015. doi:10.1093/nar/gkv402