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GENERAL
TITLE
PVHL:ELOB:ELOC IN COMPLEX WITH (2S,4R)-1-((S)-2- (CYCLOBUTANECARBOXAMIDO)-3,3-DIMETHYLBUTANOYL)-4-HYDROXY-N-(4-(4- METHYLTHIAZOL-5-YL)BENZYL)PYRROLIDINE-2-CARBOXAMIDE (LIGAND 18)
DATE LAST MODIFIED
7 Feb 2018
RELEASE
20 Sept 2017
OBSOLETE
CLASSIFICATION
LIGASE
EXPERIMENT TYPE
X-RAY DIFFRACTION
SPACE GROUP
P 41 2 2
RESOLUTION RANGE HIGH
2.1
RESOLUTION RANGE LOW
49.5
PUBMED ID
DOI
10.1021/ACS.JMEDCHEM.7B00675

Chains

Structure ChainTarget ProteinGeneExpression SystemOrganismSynonymsActions
Q15370 ELOB, TCEB2 ESCHERICHIA COLI HUMAN ELOB,ELONGIN 18 KDA SUBUNIT,RNA POLYMERASE II TRANSCRIPTIONFACTOR SIII SUBUNIT B,SIII P18,TRANSCRIPTION ELONGATION FACTOR BPOLYPEPTIDE 2 HUMAN
ELOB,ELONGIN 18 KDA SUBUNIT,RNA POLYMERASE II TRAN ...
Mutations
Q15369 ELOC, TCEB1 ESCHERICHIA COLI HUMAN ELOC,ELONGIN 15 KDA SUBUNIT,RNA POLYMERASE II TRANSCRIPTIONFACTOR SIII SUBUNIT C,SIII P15,TRANSCRIPTION ELONGATION FACTOR BPOLYPEPTIDE 1 HUMAN
ELOC,ELONGIN 15 KDA SUBUNIT,RNA POLYMERASE II TRAN ...
Mutations
P40337 VHL ESCHERICHIA COLI HUMAN PROTEIN G7,PVHL HUMAN
PROTEIN G7,PVHL
Mutations
Q15370 ELOB, TCEB2 ESCHERICHIA COLI HUMAN ELOB,ELONGIN 18 KDA SUBUNIT,RNA POLYMERASE II TRANSCRIPTIONFACTOR SIII SUBUNIT B,SIII P18,TRANSCRIPTION ELONGATION FACTOR BPOLYPEPTIDE 2 HUMAN
ELOB,ELONGIN 18 KDA SUBUNIT,RNA POLYMERASE II TRAN ...
Mutations
Q15369 ELOC, TCEB1 ESCHERICHIA COLI HUMAN ELOC,ELONGIN 15 KDA SUBUNIT,RNA POLYMERASE II TRANSCRIPTIONFACTOR SIII SUBUNIT C,SIII P15,TRANSCRIPTION ELONGATION FACTOR BPOLYPEPTIDE 1 HUMAN
ELOC,ELONGIN 15 KDA SUBUNIT,RNA POLYMERASE II TRAN ...
Mutations
P40337 VHL ESCHERICHIA COLI HUMAN PROTEIN G7,PVHL HUMAN
PROTEIN G7,PVHL
Mutations
Q15370 ELOB, TCEB2 ESCHERICHIA COLI HUMAN ELOB,ELONGIN 18 KDA SUBUNIT,RNA POLYMERASE II TRANSCRIPTIONFACTOR SIII SUBUNIT B,SIII P18,TRANSCRIPTION ELONGATION FACTOR BPOLYPEPTIDE 2 HUMAN
ELOB,ELONGIN 18 KDA SUBUNIT,RNA POLYMERASE II TRAN ...
Mutations
Q15369 ELOC, TCEB1 ESCHERICHIA COLI HUMAN ELOC,ELONGIN 15 KDA SUBUNIT,RNA POLYMERASE II TRANSCRIPTIONFACTOR SIII SUBUNIT C,SIII P15,TRANSCRIPTION ELONGATION FACTOR BPOLYPEPTIDE 1 HUMAN
ELOC,ELONGIN 15 KDA SUBUNIT,RNA POLYMERASE II TRAN ...
Mutations
P40337 VHL ESCHERICHIA COLI HUMAN PROTEIN G7,PVHL HUMAN
PROTEIN G7,PVHL
Mutations
Q15370 ELOB, TCEB2 ESCHERICHIA COLI HUMAN ELOB,ELONGIN 18 KDA SUBUNIT,RNA POLYMERASE II TRANSCRIPTIONFACTOR SIII SUBUNIT B,SIII P18,TRANSCRIPTION ELONGATION FACTOR BPOLYPEPTIDE 2 HUMAN
ELOB,ELONGIN 18 KDA SUBUNIT,RNA POLYMERASE II TRAN ...
Mutations
NGL Viewer is used for the molecular visualization.
  • AS Rose, AR Bradley, Y Valasatava, JM Duarte, A Prlić and PW Rose. NGL viewer: web-based molecular graphics for large complexes. Bioinformatics: bty419, 2018. doi:10.1093/bioinformatics/bty419
  • AS Rose and PW Hildebrand. NGL Viewer: a web application for molecular visualization. Nucl Acids Res (1 July 2015) 43 (W1): W576-W579 first published online April 29, 2015. doi:10.1093/nar/gkv402