5UPF

3D Structure View

CAVITIES

STRUCTURE SETTINGS

LIGANDS

Bioassembly 5UPF_1

Chain 5UPF_A

Chain 5UPF_B

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GENERAL

TITLE

CRYSTAL STRUCTURE OF HUMAN NAMPT WITH ISOINDOLINE UREA INHIBITOR COMPOUND 53

DATE LAST MODIFIED

21 Mar 2018

RELEASE

28 Jun 2017

OBSOLETE

CLASSIFICATION

TRANSFERASE/TRANSFERASE INHIBITOR

EXPERIMENT TYPE

X-RAY DIFFRACTION

SPACE GROUP

P 1 21 1

RESOLUTION RANGE HIGH

1.69

RESOLUTION RANGE LOW

82.74

PUBMED ID

DOI

10.1016/J.BMCL.2017.06.018

PDBe

LIGANDS

Structure Chain	Target Protein	Gene	Expression System	Organism	Synonims	Actions
	P62937	NAMPT, PBEF, PBEF1	MAMMALIA	HUMAN	NAMPT,PRE-B-CELL COLONY-ENHANCING FACTOR 1,PRE-B C ...
	P12956	NAMPT, PBEF, PBEF1	MAMMALIA	HUMAN	NAMPT,PRE-B-CELL COLONY-ENHANCING FACTOR 1,PRE-B C ...

NGL Viewer is used for the molecular visualization.

AS Rose, AR Bradley, Y Valasatava, JM Duarte, A Prlić and PW Rose. NGL viewer: web-based molecular graphics for large complexes. Bioinformatics: bty419, 2018. doi:10.1093/bioinformatics/bty419
AS Rose and PW Hildebrand. NGL Viewer: a web application for molecular visualization. Nucl Acids Res (1 July 2015) 43 (W1): W576-W579 first published online April 29, 2015. doi:10.1093/nar/gkv402