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TITLE
STRUCTURE OF PRMT5:MEP50 IN COMPLEX WITH LLY-283, A POTENT AND SELECTIVE INHIBITOR OF PRMT5, WITH ANTITUMOR ACTIVITY
EXPRESSION SYSTEM(S)
SPODOPTERA FRUGIPERDA ,
EXPERIMENT TYPE
X-RAY DIFFRACTION
ORGANISM(S)
HOMO SAPIENS ,
CLASSIFICATION
TRANSFERASE
SPACE GROUP:
I 2 2 2
RESOLUTION RANGE HIGH:
2.8
RESOLUTION RANGE LOW:
61
DOI:
10.1021/ACSMEDCHEMLETT.8B00014
EM DATA RESOURCE:
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DATE DEPOSITED:
2018-02-27 00:00:00
DATE RELEASED:
2018-05-16 00:00:00
DATE REVISED:
2018-08-08 00:00:00
BIOLOGICAL ASSEMBLY:
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3D Structure - 6CKC

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6CKC_B
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Chains

Structure ChainTarget ProteinGeneExpression SystemOrganismSynonyms
6CKC_B Q9BQA1 WDR77, MEP50, WD45, HKMT1069, NBLA10071 SPODOPTERA FRUGIPERDA HUMAN MEP-50,ANDROGEN RECEPTOR COFACTOR P44,WD REPEAT-CONTAININGPROTEIN 77,P44/MEP50
6CKC_A O14744 PRMT5, HRMT1L5, IBP72, JBP1, SKB1 SPODOPTERA FRUGIPERDA HUMAN 72 KDA ICLN-BINDING PROTEIN,HISTONE-ARGININE N-METHYLTRANSFERASE PRMT5,JAK-BINDING PROTEIN 1,SHK1 KINASE-BINDINGPROTEIN 1 HOMOLOG,SKB1HS