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GENERAL
TITLE
CRYSTAL STRUCTURE OF BCL-2 IN COMPLEX WITH THE NOVEL ORALLY ACTIVE INHIBITOR S55746
DATE LAST MODIFIED
14 Nov 2018
RELEASE
7 Nov 2018
OBSOLETE
CLASSIFICATION
APOPTOSIS
EXPERIMENT TYPE
X-RAY DIFFRACTION
SPACE GROUP
P 21 21 21
RESOLUTION RANGE HIGH
1.39
RESOLUTION RANGE LOW
42.5
PUBMED ID
DOI
10.18632/ONCOTARGET.24744
PDBe
LIGANDS
Chains
Structure Chain | Target Protein | Gene | Expression System | Organism | Synonims | Actions |
---|---|---|---|---|---|---|
Q6NAM1 | BCL2, BCL2L1, BCL2L, BCLX | ESCHERICHIA COLI BL21(DE3) | HUMAN | BCL2-L-1,APOPTOSIS REGULATOR BCL-X |
NGL Viewer is used for the molecular visualization.
- AS Rose, AR Bradley, Y Valasatava, JM Duarte, A Prlić and PW Rose. NGL viewer: web-based molecular graphics for large complexes. Bioinformatics: bty419, 2018. doi:10.1093/bioinformatics/bty419
- AS Rose and PW Hildebrand. NGL Viewer: a web application for molecular visualization. Nucl Acids Res (1 July 2015) 43 (W1): W576-W579 first published online April 29, 2015. doi:10.1093/nar/gkv402