6LHI

3D Structure View

CAVITIES

STRUCTURE SETTINGS

LIGANDS

Bioassembly 6LHI_1

Chain 6LHI_A

Chain 6LHI_B

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GENERAL

TITLE

QUADRUPLE MUTANT (N51I+C59R+S108N+I164L) PLASMODIUM FALCIPARUM DIHYDROFOLATE REDUCTASE-THYMIDYLATE SYNTHASE (PFDHFR-TS) COMPLEXED WITH C466 (COMPOUND 42) AND NADPH

DATE LAST MODIFIED

RELEASE

9 Dec 2020

OBSOLETE

CLASSIFICATION

OXIDOREDUCTASE

EXPERIMENT TYPE

X-RAY DIFFRACTION

SPACE GROUP

P 21 21 21

RESOLUTION RANGE HIGH

2.59

RESOLUTION RANGE LOW

46.41

PUBMED ID

32294614

DOI

10.1016/J.EJMECH.2020.112263

PDBe

LIGANDS

, 23286 , 931919 , 1169600

Chains

Structure Chain	Target Protein	Gene	Expression System	Organism	Synonims	Actions
	D9N170	DHFR-TS, V1/S	ESCHERICHIA COLI	MALARIA PARASITE P. FALCIPARUM	--
	D9N170	DHFR-TS, V1/S	ESCHERICHIA COLI	MALARIA PARASITE P. FALCIPARUM	--

NGL Viewer is used for the molecular visualization.

AS Rose, AR Bradley, Y Valasatava, JM Duarte, A Prlić and PW Rose. NGL viewer: web-based molecular graphics for large complexes. Bioinformatics: bty419, 2018. doi:10.1093/bioinformatics/bty419
AS Rose and PW Hildebrand. NGL Viewer: a web application for molecular visualization. Nucl Acids Res (1 July 2015) 43 (W1): W576-W579 first published online April 29, 2015. doi:10.1093/nar/gkv402