3D Structure View
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GENERAL
TITLE
HUMAN GAMMA-SECRETASE IN COMPLEX WITH SMALL MOLECULE AVAGACESTAT
DATE LAST MODIFIED
3 Feb 2021
RELEASE
27 Jan 2021
OBSOLETE
CLASSIFICATION
MEMBRANE PROTEIN/HYDROLASE
EXPERIMENT TYPE
ELECTRON MICROSCOPY
SPACE GROUP
P 1
RESOLUTION RANGE HIGH
3.1
RESOLUTION RANGE LOW
3.1
PUBMED ID
DOI
10.1016/J.CELL.2020.11.049
PDBe
--
Chains
| Structure Chain | Target Protein | Gene | Expression System | Organism | Synonims | Actions |
|---|---|---|---|---|---|---|
| P04535 | NCSTN, KIAA0253, UNQ1874/PRO4317 | HOMO SAPIENS | HUMAN | -- | ||
| O88867 | PSEN1, AD3, PS1, PSNL1 | HOMO SAPIENS | HUMAN | PS-1,PROTEIN S182 | ||
| Q96BI3 | APH1A, PSF, CGI-78, UNQ579/PRO1141 | HOMO SAPIENS | HUMAN | APH-1A,APH-1ALPHA,PRESENILIN-STABILIZATION FACTOR | Mutations | |
| P04535 | PSENEN, PEN2, MDS033 | HOMO SAPIENS | HUMAN | PRESENILIN ENHANCER PROTEIN 2 |
NGL Viewer is used for the molecular visualization.
- AS Rose, AR Bradley, Y Valasatava, JM Duarte, A Prlić and PW Rose. NGL viewer: web-based molecular graphics for large complexes. Bioinformatics: bty419, 2018. doi:10.1093/bioinformatics/bty419
- AS Rose and PW Hildebrand. NGL Viewer: a web application for molecular visualization. Nucl Acids Res (1 July 2015) 43 (W1): W576-W579 first published online April 29, 2015. doi:10.1093/nar/gkv402